2009年博士畢業(yè)于中國(guó)科學(xué)院上海生物化學(xué)與細(xì)胞生物學(xué)研究所,美國(guó)加州大學(xué)洛杉磯分校(UCLA)博士后;回國(guó)后在中國(guó)科學(xué)院上海生物化學(xué)與細(xì)胞生物學(xué)先后擔(dān)任助理研究員、副研究員。2018年9月入職中國(guó)科學(xué)院廣州生物醫(yī)藥與健康研究院,擔(dān)任研究員、課題組長(zhǎng)、博士生導(dǎo)師。為國(guó)家重點(diǎn)高層次青年人才,廣東省杰青,中國(guó)發(fā)育生物學(xué)專業(yè)委員會(huì)副秘書長(zhǎng),譜系技術(shù)與裝備研究中心執(zhí)行副主任。?
國(guó)際干細(xì)胞學(xué)會(huì)(ISSCR)會(huì)員
中國(guó)動(dòng)物學(xué)會(huì)發(fā)育生物學(xué)專業(yè)委員會(huì)副秘書長(zhǎng)
Sanofi-SIBS 2017 Distinguished Young Faculty????
ISSCR 2017 Poster Award and Travel Award??
國(guó)家級(jí)人才項(xiàng)目
中國(guó)生命科學(xué)十大進(jìn)展
中國(guó)生物信息學(xué)十大進(jìn)展
2025
1.?Chen,C.,Liao,Y.,Zhu,M.,Wang,L.,Yu,X.,Li,M.,Peng,G.*,2025. Dual-nuclease single-cell lineage tracing by Cas9 and Cas12a. Cell Reports?44,115105.
2.?Meng,X.,Li,W.,Xu,J.,Yao,Y.,Gong,A.,Yang,Y.,Qu,F.,Guo,C.,Zheng,H.,Cui,G.*,Suo,S.*,Peng,G.*,2025. Spatiotemporal transcriptome atlas of developing mouse lung. Science Bulletin S2095927325002403.
3.?Zhang,G.,Zhang,X.,Pan,W.,Chen,X.,Wan,L.,Liu,C.,Yong,Y.,Zhao,Y.,Sang,S.,Zhang,L.,Yao,S.,Guo,Y.,Wang,M.,Wang,X.,Peng,G.*,Yan,X.*,Wang,Y.*,Zhang,M.*,2025. Dissecting the Spatial and Single‐Cell Transcriptomic Architecture of Cancer Stem Cell Niche Driving Tumor Progression in Gastric Cancer. Advanced Science?2413019.
4.?Guo,C.-K.,Xia,C.-R.,Peng,G.*,Cao,Z.-J.*,Gao,G.*,2025. Learning Phenotype Associated Signature in Spatial Transcriptomics withPASSAGE. Small Methods?e2401451.
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2024
5.?Jiang,F.,Wang,H.,Li,Z.,Cui,G.,Peng,G.*,2024. Leveraging spatial multiomics to unravel tissue architecture in embryo development. Trends in Genetics S0168952524002713. ?(Review)
6.?Fan,Y.,Bian,X.,Meng,X.,Li,L.,Fu,L.,Zhang,Yanan,Wang,L.,Zhang,Yan,Gao,D.,Guo,X.,Lammi,M.J.,Peng,G.*,Sun,S.*,2024. Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integration. Annals of the Rheumatic Diseases?83,926–944.
7.?Wang,Z.,Li,Z.,Luan,T.,Cui,G.,Shu,S.,Liang,Y.,Zhang,K.,Xiao,J.,Yu,W.,Cui,J.,Li,A.*,Peng,G.*,Fang,Y.*,2024. A spatiotemporal molecular atlas of mouse spinal cord injury identifies a distinct astrocyte subpopulation and therapeutic potential of IGFBP2. Developmental Cell?59,2787-2803.e8.
8.?Zou,S.,Peng,G.*,Ma,Z.*,2024. Surface-Functionalizing Strategies for Multiplexed Molecular Biosensing: Developments Powered by Advancements in Nanotechnologies. Nanomaterials. (Review)
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2023
9.?Qu,F.,Li,W.,Xu,J.,Zhang,R.,Ke,J.,Ren,X.,Meng,X.,Qin,L.,Zhang,J.,Lu,F.,Zhou,X.,Luo,X.,Zhang,Z.,Wang,M.,Wu,G.,Pei,D.,Chen,J.,Cui,G.*,Suo,S.*,Peng,G.*,2023. Three-dimensional molecular architecture of mouse organogenesis. Nat Commun?14,4599.
10.?Jiang,F.,Zhou,X.,Qian,Y.,Zhu,M.,Wang,L.,Li,Z.,Shen,Q.,Wang,M.,Qu,F.,Cui,G.,Chen,K.,Peng,G.*,2023. Simultaneous profiling of spatial gene expression and chromatin accessibility during mouse brain development. Nat Methods?20,1048–1057.
11.?Xu,H.J.,Yao,Y.,Yao,F.,Chen,J.,Li,M.,Yang,X.,Li,S.,Lu,F.,Hu,P.,He,S.*,Peng,G.*,Jing,N.*,2023. Generation of functional posterior spinal motor neurons from hPSCs-derived human spinal cord neural progenitor cells. Cell Regen?12,15.
12.?Meng,X.,Cui,G.*,Peng,G.*,2023. Lung development and regeneration: newly defined cell types and progenitor status. Cell Regen?12,5. (Review)
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2022
13.?Chen,C.,Liao,Y.,Peng,G.*,2022. Connecting past and present: single-cell lineage tracing. Protein Cell 13,790–807. (Review)
14.?Cui,G.,Feng,S.,Yan,Y.,Wang,L.,He,X.,Li,X.,Duan,Y.,Chen,J.,Tang,K.,Zheng,P.,Tam,P.P.L.,Si,W.,Jing,N.,Peng,G.*,2022. Spatial molecular anatomy of germ layers in the gastrulating cynomolgus monkey embryo. Cell Reports?40,111285.
15.?Wen,L.,Li,G.,Huang,T.,Geng,W.,Pei,H.,Yang,J.,Zhu,M.,Zhang,P.,Hou,R.,Tian,G.,Su,W.,Chen,J.,Zhang,D.,Zhu,P.,Zhang,W.,Zhang,X.,Zhang,N.,Zhao,Y.*,Cao,X.*,Peng,G.*,Ren,X.*,Jiang,N.*,Tian,C.*,Chen,Z.-J.*,2022. Single-cell technologies: From research to application. The Innovation?3,100342. (Review)
16.?Li,Z.,Peng,G.*,2022. Spatial transcriptomics: new dimension of understanding biological complexity. Biophysics Reports?8,119–135. (Review)
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2021
17.?Lin,J.,Wu,S.,Shen,Q.,Liu,J.,Huang,S.,Peng,G.*,Qiao,Y.*,2021. Base editing‐mediated perturbation of endogenous PKM1/2 splicing facilitates isoform‐specific functional analysis in vitro and in vivo. Cell Proliferation?54,e13096.
18.?Xia,Q.,Cui,G.,Fan,Y.,Wang,X.,Hu,G.,Wang,L.,Luo,X.,Yang,L.,Cai,Q.,Xu,K.,Guo,W.,Gao,M.,Li,Y.,Wu,J.,Li,W.,Chen,J.,Qi,H.,Peng,G.*,Yao,H.*,2021. RNA helicase DDX5 acts as a critical regulator for survival of neonatal mouse gonocytes. Cell Proliferation?54,e13000.
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2020
19.?Peng,G.*,Cui,G.,Ke,J.,Jing,N.*,2020. Using Single-Cell and Spatial Transcriptomes to Understand Stem Cell Lineage Specification During Early Embryo Development. Annu. Rev. Genom. Hum. Genet. 21,163–181. ?(Review)
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2019
20.?Liu,Q.,Liu,K.,Cui,G.,Huang,X.,Yao,S.,Guo,W.,Qin,Z.,Li,Y.,Yang,R.,Pu,W.,Zhang,L.,He,L.,Zhao,H.,Yu,W.,Tang,M.,Tian,X.,Cai,D.,Nie,Y.,Hu,S.,Ren,T.,Qiao,Z.,Huang,H.,Zeng,Y.A.,Jing,N.,Peng,G.*,Ji,H.*,Zhou,B.*,2019. Lung regeneration by multipotent stem cells residing at the bronchioalveolar-duct junction. Nat Genet 51,728–738.
21.?Peng,G.*,Suo,S.,Cui,G.,Yu,F.,Wang,R.,Chen,J.,Chen,S.,Liu,Z.,Chen,G.,Qian,Y.,Tam,P.P.L.,Han,J.-D.J.*,Jing,N.*,2019. Molecular architecture of lineage allocation and tissue organization in early mouse embryo. Nature?572,528–532.
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完整論文情況Google?scholar:?https://scholar.google.com/citations?user=s7XddBgAAAAJ
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