教育經(jīng)歷：

2003.09－2007.06：華南師范大學(xué)，生命科學(xué)學(xué)院，理學(xué)學(xué)士

工作經(jīng)歷：

2023.01至今：中國科學(xué)院廣州生物醫(yī)藥與健康研究院，高級實驗師

2007.08-2022.12：中國科學(xué)院廣州生物醫(yī)藥與健康研究院，助理研究員

1、胚胎工程與動物克隆

2、顯微操作技術(shù)應(yīng)用

1、 國家重點研發(fā)計劃,代謝紊亂條件性敲除豬模型的建立及發(fā)病機(jī)理研究,2022-01 至 2026-12,280萬元,在研,參與

2、海南省重大科技計劃項目,五指山豬實驗動物模式化研究,2021-12 至 2024-12,200萬元,在研,參與

3、廣州市科技計劃項目,基因編輯豬重大腦疾病模型的制備與研究,2020-04 至 2023-03,1000萬元,在研,參與

4、國家自然科學(xué)基金委員會,聯(lián)合基金項目,基于人多能干細(xì)胞及器官缺陷豬模型進(jìn)行人源 心臟異種再造的研究,2024-01-01 至 2027-12-31,262萬元,在研,參與

1、大動物基因修飾技術(shù)研究及基因修飾動物模型的建立,廣州市人民政府,廣州市科學(xué)技術(shù)進(jìn)步獎一等獎,2015(賴良學(xué);樊娜娜;楊化強(qiáng);趙本田;歐陽振;劉朝明;趙宇;楊東山;鄧為;黃黎珍;肖磊;顧為望) (科研獎勵)

2、豬基因突變技術(shù)創(chuàng)新及基因修飾豬模型的建立,廣東省人民政府,科技進(jìn)步,省部一等獎,2016(賴良學(xué);樊娜娜;楊化強(qiáng);顧為望;肖磊;杜玉濤;黃黎珍;陳霽君;商周春;楊東山;趙本田;

歐陽振;劉朝明;趙宇;鄧為) (科研獎勵)

1. Degong Ruan #,Jiangyun Peng#,Xiaoshan Wang #,?Zhen Ouyang?#,Qingjian Zou,Yi Yang,Fangbing Chen,Weikai Ge,Han Wu,Zhaoming Liu,Yu Zhao,Bentian Zhao,Quanjun Zhang,Chengdan Lai,Nana Fan,Zhiwei Zhou,Qishuai Liu,Nan Li,Qin Jin,Hui Shi,Jingke Xie,Hong Song,Xiaoyu Yang,Jiekai Chen,Kepin Wang *,Xiaoping Li *,Liangxue Lai*. XIST Derepression in Active X Chromosome Hinders Pig Somatic Cell Nuclear Transfer. Stem Cell Reports. 2018 Feb 13;10(2):494–508.IF:7.294

2. Qingjian Zou#,Xiaomin Wang#,Yunzhong Liu#,?Zhen Ouyang#,Haibin Long,Shu Wei,Jige Xin,Bentian Zhao,Sisi Lai,Jun Shen,Qingchun Ni,Huaqiang Yang,Huilin Zhong,Li Li,Minhua Hu,Quanjun Zhang,Zhidong Zhou,Jiaxin He,Quanmei Yan,Nana Fan,Yu Zhao,Zhaoming Liu,Lin Guo,Jiao Huang,Guanguan Zhang,Jun Ying*,Liangxue Lai*,Xiang Gao*. Generation of gene-target dogs using CRISPR/Cas9 system. Journal of Molecular Cell Biology,Volume 7,Issue 6,December 2015,Pages 580–583.IF:8.185

3.?歐陽振.邱楊.吳嘉妮.余瑤章.龔莉紅.李海航.?幾種天然材料對茶多酚和咖啡因的吸附與分離特性.?科技導(dǎo)報. 2009,27(08)

非第一作者論文

1. Yanhui Liang,Jingke Xie,Quanjun Zhang,Xiaomin Wang,Shixue Gou,Lihui Lin,Tao Chen,Weikai Ge,Zhenpeng Zhuang,Meng Lian,Fangbing Chen,Nan Li,Zhen Ouyang,Chengdan Lai,Xiaoyi Liu,Lei Li,Yinghua Ye,Han Wu,Kepin Wang,and Liangxue Lai. AGBE: a dual deaminase-mediated base editor by fusing CGBE with ABE for creating a saturated mutant population with multiple editing patterns. Nucleic Acids Res. 2022 May 20;50(9):5384–5399. IF:19.16

2. Yanling Zhu,Zhishuai Zhang,Nana Fan,Ke Huang,Hao Li,Jiaming Gu,Quanjun Zhang,Zhen Ouyang,Tian Zhang,Jun Tang,Yanqi Zhang,Yangyang Suo,Chengdan Lai,Jiaowei Wang,Junwei Wang,Yongli Shan,Mingquan Wang,Qianyu Chen,Tiancheng Zhou,Liangxue Lai.Guangjin Pan. Generating functional cells through enhanced interspecies chimerism with human pluripotent stem cells. Stem Cell Reports. 2022 May 10;17(5):1059–1069. IF:7.294

3. Sen Yan,Zhuchi Tu,Zhaoming Liu,Nana Fan,Huiming Yang,Su Yang,Weili Yang,Yu Zhao,Zhen Ouyang,Chengdan Lai,Huaqiang Yang,Li Li,Qishuai Liu,Hui Shi,Guangqing Xu,Heng Zhao,Hongjiang Wei,Zhong Pei,Shihua Li,Liangxue Laiand Xiao-Jiang Li. Cell. 2018 May 3;173(4):989–1002.e13.IF: 66.85

4. Xiaoqing Zhou,Jige Xin,Nana Fan,Qingjian Zou,Jiao Huang,Zhen Ouyang,Yu Zhao,Bentian Zhao,Zhaoming Liu,Sisi Lai,Xiaoling Yi,Lin Guo,Miguel A Esteban,Yangzhi Zeng,Huaqiang Yang,Liangxue Lai. Generation of CRISPR/Cas9-mediated gene-targeted pigs via somatic cell nuclear transfer. Cellular and Molecular Life Sciences volume 72,pages1175–1184 (2015) .IF: 9.207?

5. Dongshan Yang,Huaqiang Yang,Wei Li,Bentian Zhao,Zhen Ouyang,Zhaoming Liu,Yu Zhao,Nana Fan,Jun Song,Jiangtian Tian,Feng Li,Jifeng Zhang,Lin Chang,Duanqing Pei,Y Eugene Chen,Liangxue Lai. Generation of PPARγ mono-allelic knockout pigs via zinc-finger nucleases and nuclear transfer cloning. Cell Research volume 21,pages979–982 (2011).IF: 46.297?

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