教育經(jīng)歷：

2009.09 至2013.06，隴東學(xué)院，生物科學(xué)，學(xué)士

2014.09 至2016.06，蘭州大學(xué)，發(fā)育生物學(xué)，碩士

2016.09 至2021.06，蘭州大學(xué)，動物學(xué)，博士

工作經(jīng)歷：

2021.09至2024.08，中國科學(xué)院廣州生物醫(yī)藥與健康研究院，博士后

2024.09至2024.12，中國科學(xué)院廣州生物醫(yī)藥與健康研究院，助理研究員

2025.01至今 中國科學(xué)院廣州生物醫(yī)藥與健康研究院，副研究員

專注于神經(jīng)退行性疾病及神經(jīng)系統(tǒng)損傷的再生醫(yī)學(xué)研究，主要通過基因編輯技術(shù)改造人源誘導(dǎo)多能干細胞（human iPSCs, hiPSCs），開發(fā)新型治療策略，應(yīng)用于肌萎縮側(cè)索硬化癥（ALS）、帕金森?。?/span>PD）等神經(jīng)退行性疾病，以及脊髓損傷和腦卒中等神經(jīng)系統(tǒng)損傷的治療。

1.? Jiaowei Wang^#,Wenguang Xie^#,Nan Li^#,Wenjuan Li^#,Zhishuai Zhang^#,Nana Fan,Zhen Ouyang,Yu Zhao,Chengdan Lai,Hao Li,Mengqi Chen,Longquan Quan,Yunpan Li,Yu Jiang,Wenqi Jia,Lixin Fu,Md Abdul Mazid,Yanling Zhu,Patrick H Maxwell,Guangjin Pan*,Miguel A Esteban*,Zhen Dai* and?Liangxue Lai*,?Generation of a humanized mesonephros in pigs from induced pluripotent stem cells via embryo complementation,?Cell Stem Cell,2023,30(9):1235-1245.

2.? Ting Li *,Ting Xu,Jin Zhao,Hao Gao,Wenguang Xie, Depletion of iNOS-positive inflammatory cells decelerates neuronal degeneration and alleviates cerebral ischemic damage by suppressing the inflammatory response, Free Radical Biology and Medicine,2022,181(2022)209–220.

3.? Wenguang Xie^#,Xiao-Ting Gong^#,Xiaofeng Cheng^#,Jingjing Cao*,Jin Zhao,Hao-Li Zhang*,and Shengxiang Zhang*, LIMPID: a versatile method for visualization of brain vascular networks, Biomaterials Science,2021,9: 2658-2669.

4.? Ting Li,Jin Zhao,Wenguang Xie,Wanru Yuan,Jing Guo,Shengru Pang,Wen-Biao Gan*,Diego Gómez-Nicola* and Shengxiang Zhang*,Specific depletion of resident microglia in the early stage of stroke reduces cerebral ischemic damage, Journal of Neuroinflammation,2021,18(1):81.

5.? Xiao-Ting Gong^#, Wenguang Xie^#,Jing-Jing Cao*,Shengxiang Zhang*,Kanyi Pu* and Hao-Li Zhang *,NIR-emitting semiconducting polymer nanoparticles for in vivo two-photon vascular imaging, Biomaterials Science,2020,8: 2666-2672.

6. ?Na Zhang^#,Dandan Chai^#,Huifen Du,Kesheng Li*,Wenguang Xie,Xingwen Li,Rong Yang,Xiaowen Lian and Yang Xu,Expression of Reg IV and SOX9 and their correlation in human gastric cancer,BMC Cancer,2018,18:344.

7.? Zhijie Yang,Wenguang Xie,Furong Ju,Akbar khan,Shengxiang Zhang*,In vivo two-photon imaging reveals a role of progesterone in reducing axonal dieback after spinal cord injury in mice, Neuropharmacology,2016,116(116):30-37.